Targeted proteomics has gained popularity in recent years as the ability to customize and design assay panels have become main-stream. It represents an excellent approach for identifying disease biomarkers in any body fluid, including serum, plasma, urine, stool, saliva, tears, sweat, CSF, etc.
We offer a variety of comprehensive proteomic platforms to suit your research needs
- Somascan® proteomics explores 11,000 different proteins in body fluids using a library of aptamers, using a high-throughput, multiplexed format. Use of aptamers as ligands permits high sensitivity detection of proteins. Clients can submit the following numbers of samples, or any combination of these numbers (including disease and controls): 21 , 37 , 53 , 69 , 85. A variety of body fluids can be run on this platform. See platform details here. See examples of manuscripts from Core.
- Olink® proteomics explores up to 1196 different proteins in any body fluid using Proximity Extension Assay (PEA) technology. Olink® Target 96 enables high-throughput, multiplex immunoassays of proteins using minimal volumes of serum, plasma, or almost any other type of biological sample. Up to 1196 proteins are measured for 88 samples plus 8 control samples in each run. Focused panels for Cancer, Cardiovascular, Inflammatory, Infectious, and Metabolic diseases are also available. See platform details here. See examples of manuscripts from Core.
- The Luminex® platform detects up to 50 proteins (including cytokines, chemokines, growth factors, etc.) in any body fluid or tissue lysate in a 96-well plate using magnetic beads and a CCD camera. See platform details at: EMD Millipore, ThermoFisherScientific, and BioRad. See examples of manuscripts from Core.
- The Meso Scale Discovery pelectrochemiluminescence platform allows screening of >100 different proteins (including cytokines, chemokines, growth factors, etc.) in any body fluid or tissue lysate, over a >4-log dynamic range. Detection sensitivity far exceeds ELISA assays, in the range of fg/ml. See platform details here. See examples of manuscripts from Core.
- Quantibody® microarrays from Raybiotech allow screening of 10 to >1000 different proteins (including cytokines, chemokines, growth factors, etc.) in any body fluid or tissue lysate. Focused panels for Cancer, Cardiovascular, Inflammatory, Infectious, Metabolic diseases are also available. See platform details here. See examples of manuscripts from Core.
- ELISA assays for quantifying a single protein biomarker in large numbers of clinical samples. We offer ELISA services from any vendor, for > 5000 targets.